One of customer had the Xentry error 2221-45 No access authorization when running Mercedes MB SD Connect C4 2016.07V Xentry diagnostic software. Here is the final solution provided by OBDII365.com engineer.
（2221-45） No access authorization for XENTRY Diagnostic was found on the server. You must contact the User Help Disk.
Solution from obd365 engineer:
Browse to C:\Mercedes-Benz\Xentry\fusoko\eclipse\plugins folder, delete com.daimler_xentry.diagservice_1.6_0.2016.07181047 file.
2. If you running Windows 8 hard drive,then
Browse to C:\Program Files\Mercedes-Benz\Xentry\fusoko\eclipse\plugins folder,
Delete com.daimler.xentry.diagservice_18.104.22.168607151427 file